Research Achievements:
Demonstrated that dermal exposure of hexachlorocyclohexane (HCH) could alter testicular enzymes, decrease serum testosterone and abnormal sperm morphology and activity resulting in adverse effects on reproductive functions of mammals exposed to this pesticide. Possible damaging potential of HCH was indicated by the inhibition of testicular plasma membrane bound enzymes.

Oral exposure studies on carbofuran as well as carbaryl a broad spectrum, long lasting insecticides provided first hand information on the reproductive toxicity of these xenobiotics.

Study on acrolein, one of the most toxic alkenal revealed that even its low concentrations inhibit proteins of the liver plasma membrane and appears to be the major cause of its toxicity.

Investigations on Ancylostoma ceylanicum, a human hookworm revealed that significant inhibition of liver plasma membrane bound enzymes leading to changes in structural and functional organization of membrane may be the cause of hepatotoxic manifestations. 

Demonstrated in vivo effects of Dibutyltin dichloride(DBT),that could alter liver plasma membrane bound enzymes and lipids.


Research Interests:
Structural and functional mechanism of parasitic infection, cause and remedy. 
Interaction of xenobiotics with plasma membrane, reproduction and fertility.
Immunological evaluation of industrial toxicants and allergens.


Research Experience:
Fertility / Infertility evaluation for the development of antifertility drugs. 
Xenobiotic metabolism studies in relation with alterations in plasma membrane.
Use of plasma membrane of different organs as a model for interaction of xenobiotics. 
Studies on structural and functional mechanism of parasitic infection.
Immunological parameters for evaluation of industrial toxicants and allergens

Awards/Honours/ Distinctions:
Membership of Professional Bodies
Society of Toxicology
India Indian Society for Parasitology
Society of Biological Chemists, India